Karen Clone A is one of Karen Minamino's clones which appear in Episode 3 of Aika R-16: Virgin Mission, Deep Blue Girl. She inhabits an abandoned undersea lab together with the rest of her sisters. She wears a skimpy purple, barely hip length, chemise with a little white bow on the chest. Her panties also fashion another ribbon, this time blue, above the crotch. The outfit is completed with a pair of over the calf black socks, which all regular sized clones use, without any shoes. Karen Clone A is the first clone to appear as Aika Sumeragi and Eri Shinkai are inspecting the undersea lab. She startles both girls while they are focused inspecting one of the lab's computers, causing Eri to fall to the ground in shock.

After the initial surprise, Aika and Eri fall back and realize they are actually surrounded by the clones, which don't seem initially hostile. They then try to communicate with them, but their efforts are cut short when Karen Clone A turns aggresive and lounges towards them.

Indeed, from one moment to the other and without previous warning, the clone crouches and then jumps acrobatically in the air, even doing a flip mid-flight before landing right in front of Aika and Eri. She then strikes at the Salvager with a knife, but Aika is already on guard and easily evades the attack. She then counter attacks with a brutal kick below the girl's breasts, right in the solar plexus, which causes the clone to scream and expectorate profusely in all directions as she is violently thrown backwards.

The girls is then sent flying pretty much all the way back to her initial position, her whole body bent in response to the blow, ass sticking out.