Still as a child, Integra inherited her position as Bureau Director of the Hellsing Organization after the death of her father, Arthur Hellsing. Her uncle tried to kill her to become his brother's successor, but she was saved by Hellsing's vampire, Alucard, and she succeeded in killing Richard Hellsing. Years later, as a 22-year-old British noblewoman, a member of the Protestant Knights and the leader of Hellsing, she protects England and her Queen against the forces of the supernatural.