The news had reported a new infection called "Devil's angels eyes" infection (shit huh?), it actually is a infection that can completely change your body. The first stage will be your mouth will start to tingle and your attitude starts to change.

The second stage, your mind gets completely out of control and your behavior becomes erratic and aggresive. And soon enough be a c@nn!b@l. and you can't control yourself much.

The third stage.. Your face dissapears. Only left with a disturbing eye and mouth. Your body becomes messy and cracks will be all over your body. You don't have any control over your body and you are considered maniac.

In Tenjiku... Izana's already on third stage infection. But he's fine.