Otonose Kanade, Juufuutei Raden, Todoroki Hajime, Ichijou Ririka, and Hiodoshi Ao are female Virtual YouTubers affiliated with Hololive DEV_IS, a branch of hololive productions. They're a part of the unit ReGLOSS.

Kanade's an aspiring musician. Anything she dislikes immediately puts a frown on her face, showing she still retains a childish side
Raden loves art and culture of all kinds
Hajime's childish, energetic
Ririka's cutely, ladylike, cheerful
Ao's calm, chick magnet.

They're all humans.