In her true form, Android 21's skin turns pink, her ears pointed, her eyes red with black sclera and gains a tail. Her attire changes to a black tube top, keeping the black arm sleeves, and also gaining white baggy pants. It's noted that she mostly resembles a Majin in this form.

Android 21 was shown to trust 18, passing on the soul to her. In spite of this, she is still ravaged by her hunger and has a natural desire to eat her allies, leading 21 to fear herself.