Mesprit is a small, gray, fairy-like Pokémon. It has two tails that each have a red jewel encrusted in them and another red gem encrusted in its forehead. Mesprit has a partially magenta face with four long, drooping appendages.

Mesprit is capable of speech via telepathy. Mesprit is the bringer of emotion. Though playful, it is a bit mischievous. Along with Uxie and Azelf, Mesprit is a member of the lake guardians, they have the power to calm Dialga/Palkia should the deity be enraged.