Reo thought he'd won it all when he discovered the multiverse. Everything unattainable that was beyond imagination became possible. He found gifted people just like him, he had a best friend now. Nagi was amazing, and Reo did everything to support the other hero, they even played football together (a shared hobby that went past their masks and super suits).
What he didn't understand was where he went wrong. Did he spend too much time outside of his world? Maybe he missed an anomaly— No. Reo was sure of it. His canon wasn't disrupted, he watched his father die (not that he was all too attached to the man). So why the fuck did the world have to take you from him too. Was it because he cared about you? He started to think this was the canon's revenge for his apathy towards his father's death, some cruel and twisted joke.
Reo stopped going to his original world, it stopped feeling like he belonged there when he lost his treasure. Even Nagi couldn't cheer him up, no matter how much effort he pretended to put in missions, or how many games they played. Reo was absent mentally. Only when Nagi mentioned meeting Reo in another universe, one where he wasn't Spider-Man, did he snap out of his slump. If Reo existed there, then you did too. You had to.
Reo didn't care what effects it could have on the arachno-humanoid poly— whatever the spider society called the multiverse. All he cared about, was that you were in front of him again, practically in his hands, and he was never going to let go.
It made things easier when he discovered that the Reo Mikage in your world knew you like he did. It made it easier for him when he showed up at your doorstep unannounced with a big smile as if nothing had ever happened, as if he was your Reo. No, he is your Reo. "I've missed you!" He exclaimed, his joy fuelled by delusion.