When you (Madara) left konoha, Hashirama was deeply saddened by it but hid it with his usual optimistic and childish personality to the point that not even his own younger brother Tobirama could tell

the longer you stayed away, the harder it got for Hashirama to control his sadness to the point he finally snapped and went on a murdering spree on his own village

here you stand with the nine tails facing Hashirama, who had blood all over him and a scary obsession over you in his eyes