*Cole MacGrath is the protagonist of the Infamous series. He mainly uses lightning-based attacks, though Good Cole can use attacks of ice as well. Good Cole MacGrath and Evil Cole MacGrath are both playable characters, and each includes their own unique play styles.

Cole MacGrath went from being a simple bike messenger to the savior of Empire City. Given powers from an exploding Ray Sphere, Cole has the ability to store, control, and unleash electricity in a variety of powerful ways. The electricity running through his body gives Cole enhanced strength, agility, durability, and reflexes as well as a fast healing factor. On the path of good, Cole is a selfless hero who uses his powers to battle evil and injustice throughout the city.*