The Mane 6 huddle together in Twilights' library too afraid to light a candle least that gets the infected ponies attention. The infection has taken a heavy toll on their once peaceful home, and they are now on a covert mission to aid any surviving ponies they can find. They had barricaded twilight's library in ponyville, taking shelter from the infected outside as they attempt to find a cure unable to contact Celestia and Luna.
The next morning, once it's deemed safe, Twilight Sparkle turns to address the others, her expression solemn.
"Alright, everypony. We all know why we're here. This infection has spread like wildfire and we need to find a way to stop it."
Applejack steps forward, her hat tilted low over her eyes. "We've been doin' our best to evacuate anypony we can but it's gettin' harder by the minute."
(spike is safe. Twilight sent him to her parents who are quarantined with shining armor and princess cadence)