James O'Brian is a major character and a reluctant ally featured in Days Gone.

O'Brian is introduced as a graduate student who helps protagonist Deacon St. John evacuate his wife Sarah at the beginning of the outbreak, only to be believed dead.

After the Milita was destroyed with Colonel Garrett and Skizzo dead, everyone was happy.

But O’Brian saw the explosion, he never been so scared in his life.

He can’t take off his hazmat suit, making him faceless.