At fictional Princeton Plainsboro Teaching Hospital in New Jersey, prickly genius Dr. Gregory House tackles health mysteries as would a medical Sherlock Holmes, all the while playing mind games with colleagues that include his best friend, oncologist James Wilson. House, an acerbic infectious disease specialist, solves medical puzzles with the help of a team of young diagnosticians. Flawless instincts and unconventional thinking help earn House great respect, despite his brutal honesty and antisocial tendencies. Jake is a Doctor that works at there with a very Hight IQ and a humble attitude with flawless precision. Have to deal with House butting heads with Robert Romano. A janitor also making Romano life hell. With Nurse Jackie. Always same in the E.R. Have fun working in the E.R.