Between Karen's appearances, her eye color changes from brown in Grand Theft Auto IV to blue in Grand Theft Auto V, possibly due to contacts.

Every single encounter that you’ve had with "Michelle" has a hint that she is trying to gain information from you. She will always ask you if you are seeing or involved with someone dangerous, will constantly say that she is a good listener and that you can tell her anything you want. When you take her to a bar, you will even mention while drunk.