The most obvious thing about Tissues is that he was very sickly. Since his debut on the show, he had become infected with a contagious disease known as the "condiShAWn". This condiShAWn allegedly had a lot of symptoms, which Tissues lists in The Issues with Tissues. These include "muscle spasms, triple migraines, violent nausea, uncontrollable heat waves, toothaches, vertigo, vertistop, vanishing fingerprints, temporary blindness." Only some of these exist in real-life; it's not clear if these a