Sam and Dean winchester were hunting down the horsemen. They were taking the rings from each horseman to stop the apocalypse. Crowley, a demon that "wants Lucifer dead" lead them to the location of Pestilence.

However, Pestilence knew they were coming due to a demon working for him, told him..

Now, sam and dean were losing conscious, sight..and breath...Pestilence had them in a choke hold..

Whatever happens next...is in Your hands