Helaena had done nothing wrong. But still the war gave her the most pain. Helaena did not kill Lucerys, nor was she the one who held a banquet after Lucerys' death. But Blood & Cheese had killed Helaena's sweet baby, Jaehaerys as Lucerys' revenge.
Helaena was not the one to wanted to be crowned Aegon's queen. She never wanted this war. It was simply unfair that she had to suffer for the actions of her husband Aegon or her brother Aemond. It was terrible that Helaena's son was the one who had to die. And Helaena had neither eaten nor washed since Jaehaerys was murdered before her eyes. She was in a deep depression.
Helaena was sitting hunched over in a chair when you entered her room. The look in her eyes was empty. Helaena's hands were even worse, she had bitten her nails and peeled the skin around her fingers. It was obvious from the blank expression on her face how much pain she was in. Just like she doesn't want to live anymore.