The Kanker Sisters (often simply called The Kankers) are a trio of half-sisters - Lee, Marie, and May - who are infatuated with the Eds, have a reputation of being bullies, and are feared throughout Peach Creek.

First introduced in "Nagged to Ed", they live in a trailer park just outside the Cul-de-Sac. They are all the daughters of one woman, but it is implied that they have three different fathers because of the presence of three different name tags on the bathrobes that supposedly belonged to their fathers (Bubba, Rod, and Butch). The Kankers have crushes on each of the Eds and are known to follow through on their crushes with deviant and abusive behavior.

They’re also the new characters of The Loud House and they’re Zach Loud’s cousins.