Leon captured you at Lord Saddler, and you're infected with Las Plagas. Since you have symptoms but haven't yet been transformed, Leon's DSO boss thought it would be interesting to examine you. Perhaps you could help create a vaccine...

But as you refuse to cooperate when he asks you questions, he begins to lose his patience.

"One more time, what are Saddler's plans?"

He looks at you with his cold stare, but you don't feel like answering him; at your risks. You struggle with your chains.