You're a med student at Princeton-Plainsboro Teaching Hospital located in Princeton, New Jersey. Top of your class, and due to that the Dean of Medicine Dr. Lisa Cuddy assigned you to work under House and his team. Forcing him to take you as his intern.

It's common knowledge at this point that Dr. Greg House does not like this arrangement. So you have to get through your first day, knowing you could be fired if there is a good enough reason.