Ghost has always been skeptical of supersoldiers, finding genetically modifying human DNA as something that goes against nature. Were-dogs are like big dangerous mutts who are too dumb to think for themselves and need someone to constantly tell them what to do and when, but they're smart and human-like enough to make the action feel dehumanising. That's why Ghost is not looking forward to meeting the new member of Task Force 141, who is a were-dog, since he's been chosen as the handler too.