My father was a sailor, my mother was a fish. Since I was little girl, I've only had one wish. A tiny dream belonged to me to be known across the seven seas. I started small, but my ambition grew, and now I'm known across the ocean blue. All my life, what I wanted to be, the fiercest monster in the deep blue sea! It's a lonely life, but the only life I would ever want for me. But I've come so far, and now I'm a star, and everyone knows me! Yes, I am number one sea beast…I am the Cala Maria!

*Cala Maria is a minor character who serves as the main antagonist of The Cuphead Show! episode, "A High Seas Adventure!". She is based on Cala Maria from the original video game.

Cala Maria is a giant mermaid (a fish-human hybrid). She looks mostly the same as her game counterpart.

In her normal form, she has a purple dead octopus as hair, pale purple skin, and turquoise eyelids. She has thin pink lips, a small and pointed nose, big blue eyes, big eyelashes and thin eyebrows. She has a turquoise fish tail and her seashell bra is now greenish-turquoise. She has two marks in each of her arms.

In her other form, her skin is greenish, her hair is messy and pointed and the tentacles of the octopus are now snakes with bright yellow eyes that are shown to mirror her expressions and her eyes are at first shown to be a bright red, but further in her debut they become yellow with slitted pupils. Her teeth are sharper, and her tongue is splitted in two in the end.

In Mugman's story, Cala wears a light blue off-the-shoulder blouse with a white loose bow on the center, a black underbust corset with dark gray laces, and a dark blue sash, a black choker around her neck, sea-green eyeshadow for makeup, a mole under her left eye, and a pastel green bow on her head.

Cala Maria appears to be hostile and dangerous, turning all the pirates into stone. She has a no-nonsense, down-to-business attitude, preferring to focus on her career as a sea monster rather than reciprocate the feelings of anyone who loves her. She is also very sassy and snarky, as shown when she flatly calls Mugman "Dinner" when he was introducing himself to her. Despite this, she is very merciful when she gave Captain Brineybeard a 10-second head start before attempting to eat him and his friends. She speaks using an ambiguous European accent.*