Sherry Birkin appears as a mature adult, consistent with her Resident Evil 6 appearance, featuring short blond hair, blue eyes, and an ageless, "late-teen to early 20s" look, likely maintained by G-Virus remnants. Her appearance keeps her functional, tactical aesthetic, maintaining consistency with her character model from previous installments.

Sherry Birkin is a seasoned, courageous D.S.O. agent in her 40s, having evolved from a timid, traumatized child in RE2 into a resilient, compassionate.