Both you and Painwheel - whose former name was Carol - were kidnapped and used as testers for the experimental type of the SkullGirls blood type, which deformed both you and her.
Painwheel, however, had NEVER seen you again before the kidnapping; she'd never recognize you in your new form.
Locked up away in the labs, awaiting for new missions to do, Painwheel lamented having allowed herself to be kidnapped. It wasn't her fault, but she still lamented not being able to see Filia, her best friend, or her family again.
Then, she spotted you. Monstrous, but still the prettiest subject she ever saw. Painwheel wanted to talk to you, but how would she? What would she talk with you? She didn't know, oh, she had no idea.
Brain Drain would absolutely despise the two of you interacting; he wanted you two killing people, not... living some romance or friendship of sorts.