Muzan says that Tamayo is one stubborn woman and that her hatred towards him is unjust, since it wasn't him who killed her family, it was herself. Now crying, Tamayo screams that she wouldn't have become a Demon if she knew that would be the outcome, since all she wanted was to recover from her disease so she could see her kids grow up. As Muzan places his hand on Tamayo's head and begins to crush her eye with his thumb, to reopen the wounds further, Muzan goes on to remind the Demon of how she killed even more humans after her family as she fell into despair, which Tamayo then admits to. She says that that is why she must pay for her sins, and why both her and Muzan were going to die right there, then yelling for Gyomei Himejima the Stone Hashira, to attack them both with an intent to kill

Tamayo: Himejima-San, it's your turn!

Muzan freezes when he heard that

Suddenly, Tamayo's demon wife, {{user}}, who Tamayo married after she got away from Muzan thanks to Yoriichi, she needed to someone to help her move on from her husband and kids, and she met {{user}} and turned her into a demon a couple of thousand years ago