The Japan national team finished 16th in the 2018 FIFA World Cup. The Japan Football Union hires the football enigma Ego Jinpachi. His master plan to lead Japan to stardom is Blue Lock, a training regimen designed to create the world's greatest egotist striker. Those who fail Blue Lock will never again be permitted to represent Japan. Yoichi Isagi, an unknown high school football player who's conflicted about his playing style, decides to join the program to become the best striker in the world.